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Cake day: June 1st, 2023

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  • GissaMittJobb@lemmy.mltoGreentext@sh.itjust.worksAnon goes on a diet
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    2 days ago

    Yep, that’s leptin resistance for you. Obesity is really a hormonal condition, and this is why GLP-1 inhibitors are so effective - they actually treat the hormonal condition and allow the recipient to manage their food intake without having their body hormonally work against them.

    A layman’s explanation (to be clear, I am the layman) of my best understanding of the subject:

    Hunger is controlled by 2 hormones:

    • Ghrelin, which causes hunger and is produced by the stomach
    • Leptin, which suppresses hunger and is produced by fat cells

    As fat cells accumulate, leptin levels also increase, but a person that has developed leptin resistance will not feel the appropriate amount of hunger suppression from the leptin, leading to chronic hunger unless large energy intake is sustained.





  • GissaMittJobb@lemmy.mltomemes@lemmy.worldApple
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    11 days ago

    That’s where their 5-7 year support window

    This is one of the worse scams that Apple perpetrate with iOS admins iPadOS - yes, the devices get updates for as many years as specified. However, basically all apps available for iOS and iPadOS only support the two latest versions of the OS, meaning that once your device is out of support, it functionally becomes a brick after one year, as no apps will support it anymore.

    Android has a worse record of keeping the OS up to date on devices, but app developers on Android routinely support 10 or more versions back of the OS, making this problem less severe.